Senior Research Scientist (Mass Spectrometry, Proteomics) Bioscience, Oncology R&D

We are recruiting for an opportunity to join the biological mass spectrometry (MS) capability within the Oncology Bioscience group in Cambridge. As a mass spectrometry Senior Research Scientist, you will be accountable for delivering robust and high quality proteomics data supporting drug discovery projects across the Oncology portfolio.

Working collaboratively with other disciplines across AstraZeneca, you will have the opportunity to really drive projects forward by implementing innovative solutions to address challenging biological questions. You should have a background in mass spectrometry and must have a strong passion for delivering data from the laboratory. You will use your strong scientific judgement, ability to analyse data, laboratory experience and communication skills to provide key contributions to experimental design and interpretation for drug discovery programmes.

About AstraZeneca

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialisation of prescription medicines for some of the world’s most serious diseases. But we’re more than one of the world’s leading pharmaceutical companies.

Site description

Granta Park, Cambridge (UK), is one of over 400 sites here at AstraZeneca, providing an environment where everyone feels comfortable and able to be themselves is at the core of AstraZeneca’s priorities. It’s important to us that you bring your full self to work every day. To help you maintain your best self, here’s a sneak peek into some of the things this site provides for you…Cambridge is one of the most exciting bioscience hotspots in the world and plays a central role in our mission to deliver life-changing medicines to patients. Granta Park has a gym, nursery, and central restaurant/coffee place as part of the science park facilities that are accessible to our staff. We also have our own bistro and deli in the AZ buildings. There are regular lunch & learn events including running clubs and after work socials on the last Friday of every month. This is our biggest and most spacious lab site with easy access from all major routes and ample car parking available - come and join us! Please be aware that towards the end of 2023 you will be required to move to our new state of the art Cambridge Biomedical Centre.

Business area

In the Oncology Business Unit we relentlessly follow the science, challenging the norm to deliver more effective treatments to patients in need. Our dedication means we purposefully push back the limits of knowledge to change the practice of medicine. To ensure no patient is left behind, no matter what stage of disease.

What you’ll do

• Develop, validate and implement MS-based proteomic approaches for application to drug discovery projects.

• Operate state-of-the-art LC-MS instrumentation and ensure high-quality data generation.

• Provide interpretation of the data, presenting key findings in a clear and concise manner while demonstrating a good understanding of its implications within the overall context of drug discovery.

• Maintain an awareness of current developments in the field and bringing forward new initiatives to improve the capability.

• Actively drive personal development with the group and independently identifying relevant opportunities.

Essential for the role

• PhD in proteomics, mass spectrometry, analytical biochemistry or a related field. Alternatively a B.Sc. or M.Sc. degree with relevant industrial laboratory experience.

• Strong theoretical understanding and practical knowledge of proteomic workflows.

• Experience with high-resolution mass spectrometry platforms including designing, optimising, and analysing reaction monitoring (PRM/MRM) based assays.

• Solid understanding of separation chemistry for peptide analysis with an experience of nano-flow UPLC.

• Evidence of a strong scientific track record and ability to lead from the bench in problem solving and the development of innovative solutions.

• Strong communication and presentation skills including the ability to work collaboratively across multidisciplinary teams.

Desirable for the role

• A knowledge of cancer biology.

• An understanding of the drug discovery process

Why AstraZeneca?

There’s no better place to make a difference to medicine, patients and society. An environment that champions diversity and collaboration, and always committed to learning, growth and development. We’re on a journey to pioneer the future of healthcare.

So, what’s next?

• Are you already considering joining the team? Good, because we can’t wait to hear from you.

• Are you ready to bring fresh thinking to the table? Brilliant! We have one seat available, and we hope it’s yours.

• If you’re curious to know more, apply today

Competitive salary package and benefits

Close Date: 28/04/2023

Where can I find out more?

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