Scientific Researcher - Structural Studies - Dr Jan Löwe

☞ Medical Research Council

View: 101

Update day: 07-05-2024

Location: Cambridge East

Category: Science Labor Pharmaceutical / Chemical / Biotech

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Job content

To work within the group of Dr Jan Löwe at the MRC Laboratory of Molecular Biology (LMB), on a programme aimed at the elucidation of molecular mechanisms of ESCRT-III-based cell division in TACK archaea such as Sulfolobus acidocaldarius. Specifically, to undertake research to investigate the polymers of CdvA, B0-B3 and in conjunction with CdvC (Vps4) using biochemical and structural methods such as cryo-EM.

Main duties:

  • To undertake research aimed at the elucidation of molecular mechanisms of ESCRT-III-based cell division in TACK archaea.
  • To identify, develop and apply a broad range of techniques to pursue the research objectives.
  • To present scientific work at seminars within the laboratory and at external meetings.
  • To contribute to laboratory-wide discussions on developments within the field.
  • Where appropriate, to draft scientific papers, and contribute to the overall preparation of research for publication.
  • To contribute to the LMB’s mission in the public engagement of science, and the translation of research findings into improvements in health care.
  • To assist in the training of PhD students and other members of the LMB.

Key responsibilities:

To plan your own work and objectives and manage your experimental work within the project along with your Supervisor.

To introduce and apply new techniques across a wide range of disciplines and to have the creativity and initiative to develop novel approaches and methods where required.

To ensure the research is carried out in accordance with good practice and in compliance with local policies and legal requirements.

To contribute to the smooth running of the group, including the effective use of resources, training of others and taking responsibility for use of communal facilities.

Working relationships:

You will report to Jan Löwe and will interact and collaborate with other Postdoctoral Scientists, Research Support staff and students, not only in your group, but also across the LMB and with external groups as necessary.

Person Specification

Academic qualifications:

These should include a PhD in a relevant subject or due to complete PhD within 6 months.

Technical skills and expertise:

Experience of and ability to perform techniques relevant to the project. Particularly useful would be experience of electron cryomicroscopy (cryo-EM) and image processing.

Track record of research:

This will include achievements, and contributions to published papers.

Other relevant evidence of:

  • Commitment.
  • Originality.
  • Ability to communicate.
  • Working with others.
The MRC is a great place to work and progress your career, be it in scientific research or the support functions.The MRC is a unique working environment where our researchers are rewarded by world class innovation and collaboration opportunities that the MRC name brings. The MRC is an excellent place to develop yourself further and a range of training & development opportunities will be available to you, including professional registration with the Science Council.

Choosing to come to work at the MRC (part of UKRI) means that you will have access to a whole host of benefits from a defined benefit pension scheme and excellent holiday entitlement to access to employee shopping/travel discounts and salary sacrifice cycle to work scheme, as well as the chance to put the MRC and UKRI on your CV in the future.

Our success is dependent upon our ability to embrace diversity and draw on the skills, understanding and experience of all our people. We welcome applications from all sections of the community irrespective of gender, race, ethnic or national origin, religion or belief, sexual orientation, disability or age. As "Disability Confident" employers, we guarantee to interview all applicants with disabilities who meet the minimum criteria for the vacancy.

UKRI supports research in areas that include animal health, agriculture and food security, and bioscience for health which includes research on animals, genetic modification and stem cell research. Whilst you may not have direct involvement in this type of research, you should consider whether this conflicts with your personal values or beliefs.

We will conduct a full and comprehensive pre-employment check as an essential part of the recruitment process on all individuals that are offered a position with UKRI. This will include a security check and an extreme organisations affiliation check.
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Deadline: 21-06-2024

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