Research Assistant/Associate - C.elegans

☞ Wren Therapeutics

View: 102

Update day: 07-05-2024

Location: Cambridge East

Category: Science Labor Pharmaceutical / Chemical / Biotech

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Job content

This is an excellent opportunity to join a thriving Cambridge Based SME as a talented Research Assistant or Associate to join its rapidly growing scientific team.

The appointee will assist in running a busy experimental laboratory and help performing C. elegans based assays that are associated with pre-clinical candidate selection and validation of new drugs for protein aggregation in protein misfolding diseases. The candidate is expected to be fully engaged in general laboratory activities, meetings, and discussions. The appointee will conduct drug discovery research projects, under the supervision of senior members of the team and will contribute to the development and application of new methodologies. The successful candidate will have a desire to play a role in discovering new treatments for debilitating diseases, while working in an innovative and fast-paced environment.

Key responsibilities are, but not limited to

  • Assist in running a busy experimental laboratory, including the growth and maintenance of different C. elegans transgenic lines
  • Help keeping record of experimental work
  • Perform a range of worm assays to test toxicity of protein aggregates and the ability of potential inhibitors to reduce such toxicity in worms
  • Support the characterisation of new C. elegans transgenic lines, as required
  • Improve existing experimental protocols and assays, while working with the program lead to develop new ones
  • Contribute to data analysis, as required
  • Mentor colleagues with less experience
  • Support the daily laboratory maintenance

Skills, qualifications and experience required

  • Masters degree in biology, biochemistry, neurobiology/neuroscience, or a related discipline, at a leading academic institution or relevant industry experience

  • Experience in low or high-throughput toxicity assays, including for drug screening

  • Experience working with C. elegans transgenic lines related to protein misfolding and aggregation is highly valuable

  • Experience working with cellular or animal models for drug discovery is a plus

  • Relevant work experience in a high-profile industrial setting is a plus

  • Knowledge of data analysis software is a plus

  • Proven skill to work in a fast paced and highly dynamic environment

  • Knowledge of biological biosafety levels.

  • Experience in assisting to run a busy C. elegans laboratory (i.e. maintenance of strains, preparation of reagents related to C. elegans biology).

What’s on Offer

Wren Therapeutics will offer the opportunity to work for a growing and successful business in the Biotech industry, a generous salary, and benefits package. If you meet the above criteria and would be interested in working for us, then please apply.

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Deadline: 21-06-2024

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