Scientist - USP - E.coli

Make your mark for patients.

We’re here because we want to build the future and transform patients’ lives for the better.

At UCB, our people are our experiences and achievements, our passion and drive. That’s why we’re looking for talented individuals with diverse backgrounds and experiences - not just the best and brightest, but those who care about making a meaningful difference in the lives of patients. We promote an environment of diversity, openness, and respect where people can make valuable contributions.

An exciting journey lies ahead. Will you join us in pushing the boundaries of what’s possible?

To strengthen our Upstream Process Sciences group, based in our UK Research and Development Site in Slough, we are looking for a highly motivated Scientist to join our Microbial Process Sciences team.

In this role, you will be involved in a range of process development activities across fermentation and primary recovery including process optimisation studies and troubleshooting investigations, evaluation of cellular responses to process operations, assessment of effects on product quality, determination of process scalability and tech transfer to GMP facilities. The ideal candidate will be an enthusiastic and proactive team player with experience of E.coli process development at both lab and pilot scale.

You like to work in an environment where you can:

• Collaborate with various process scientists (upstream and downstream) and analytical scientists as well as research and clinical manufacturing groups.
• Utilize knowledge from molecular biology, biochemical engineering, microbial process development, statistics, and cellular metabolism to aid in process development and optimization of upstream processes producing protein therapeutics.
• Learn new techniques and processes while working in a collaborative high performing team environment.

You will contribute by:

• Performing microbial process development experiments for the improvement and/or characterization of existing processes at lab and pilot scale (from 250mL to 200L).
• Identifying scale-up challenges and developing robust processes for tech transfer to manufacturing scale.
• Trending and analysing laboratory data and present results to line manager, Upstream team and at internal meetings.
• Working independently and as part of a strong team to support the group’s work.
• Providing technical expertise in upstream processing for internal customers
• Providing traceable records of lab work, experimental design and report writing.
• Aiding with reviewing, writing and updating internal procedures and documents.
• Contributing to the maintenance and housekeeping of a safe laboratory working environment, including contribution to writing and reviewing HSE risk assessments related to USP activities.

Interested? For this position you’ll need the following education, experience and skills:

• Demonstrated expertise in the operation of lab and pilot scale microbial processes, including the use of various bioreactor systems and relevant operating control software.
• Ability to design and perform process development experiments as well as excellent data interpretation, drawing of conclusions and proposals for further work.
• Ability to learn and use appropriate data management concepts and tools.
• Ability to author comprehensive and accurate protocols, reports and SOPs.
• Experience with high throughput technologies, automation, miniaturisation, statistics and/or programming is preferred.
• Experience in cGMP and large-scale manufacturing equipment and practices and with the transfer of technology to cGMP operations is preferred.
• Having a sound understanding of coli physiology is preferred

Why you should apply

At UCB, we strive to attract passionate and outstanding talents who thrive on change and are ready to bring real value to patients. Working for us you’ll discover a place where you can grow and express your full potential. We place an emphasis on innovation, collaboration and impact. Through meaningful recognition and a motivating work atmosphere, we aim to provide an optimal experience by caring about and valuing our employees – just as we do for the patients we serve.

If you believe you are the perfect match to join us on our pioneering adventure, then we invite you to apply and tell us more about your profile and motivation.

About us.

UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are around 7,600 people in all four corners of the globe, inspired by patients and driven by science.

At UCB, everything we do start with a simple question: “How will this create value for people living with severe disease?”. We are on a journey to become the patient-preferred biopharma leader by delivering medicines and solutions that improve lives. We want to ensure the creation of patient value, now and into the future, while contributing to a society where a population of 8 billion people and more should be able to live a good life within limited resources of one planet.

UCB and its subsidiaries encourage diversity and inclusion in the workplace; we are an Equal Opportunity Employer. We do not discriminate on the basis of race/color/religion/sex/national origin/veteran/disability/age/sexual orientation/gender identity.