Scientist/Research Scientist – Molecular Pharmacology

Our mission is to make a significant contribution to improving the quality of life and health of people around the world. To achieve this, we will discover, design, and develop the most innovative and effective medicines for patients worldwide, through our world-leading patent-protected technology and platform.

We are an international biopharmaceutical group focused the discovery and early development of new medicines originating from our proprietary G Protein-Coupled Receptor (GPCR) targeted StaR® technology and Structure Based Drug Design (SBDD) platform capabilities. We are advancing a broad and deep pipeline of novel medicines across multiple therapeutic areas, including neurology, immunology, gastroenterology, and inflammation diseases.

We have established partnerships with some of the world’s leading pharmaceutical companies and multiple emerging technology companies, including AbbVie, AstraZeneca, Biohaven, Genentech (Roche), GSK, Neurocrine Biosciences, Novartis, Pfizer, Takeda and Verily. Sosei Heptares is headquartered in Tokyo, Japan with corporate and R&D facilities in Cambridge, UK.

Sosei Heptares has approximately 170 employees based at its new R&D research facility at Granta Park. The size of the company ensures a transparent linkage between all activities from early discovery through to clinical development.

For more information, please visit https://soseiheptares.com/. LinkedIn: @soseiheptaresco | Twitter: @soseiheptaresco | YouTube: @soseiheptaresco

Position:

We are currently looking to strengthen our Pharmacology team and are seeking to recruit a highly motivated laboratory-based in vitro pharmacologist to join our team at Scientist or Research Scientist level (depending on experience). The Pharmacology team is responsible for both new drug target validation and supporting all drug discovery phases up to pre-clinical candidate (PCC) selection via performing assays to study pathological characteristics of GPCRs in disease.

This role will primarily involve assay development and provision of routine small/large molecule screening. In addition, you may be expected to set up and run more complex mechanism of action studies in native cellular systems.

Requirements:

The successful candidate is expected to have:

• An undergraduate degree or PhD in pharmacology or similar biological sciences, or relevant industrial experience.
• Practical laboratory experience such as mammalian cell culture, recombinant cell-based assays, primary cells/tissues.
• Prior experience working with GPCRs.
• Strong numerical and analytical ability.
• Excellent communication and interpersonal skills and demonstrated capability to operate in a collaborative and entrepreneurial environment.
• The ability to communicate clearly, both verbally and in written reports, in English.

Desirable but not essential:

• Previous experience using automation (such as automatic liquid handlers).
• Experience within neuroscience, gastro-intestinal disease or immunology therapeutic areas.
• Knowledge of techniques such as flow cytometry, imaging, radioligand binding, fluorescence-based assays.

Other information:

The successful candidate will be employed by Heptares Therapeutics Ltd, a UK wholly owned subsidiary of Sosei Group Corporation.

Applicants must be able to demonstrate proof of the right to work in the United Kingdom and expect be available to start from July 2022.

We offer a competitive salary, commensurate with qualifications and experience, and benefits package including pension and healthcare schemes.

Applications should include a CV and covering letter, providing a short description of the background to their interest in the role. Please apply through our on-line job’s portal with your application in pdf format, quoting reference number 2022-RS-MP

The closing date for applications is 28th February 2022

Sosei Heptares does not accept speculative or unsolicited CVs from agencies. All speculative or unsolicited CVs submitted without an agreement in place will be considered Sosei Heptares property and will not obligate us to pay a referral fee.