Salary: £35,845 - £40,322 a year

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Job Purpose
The post holder will join the Institute of Infection, Immunity and Inflammation MRC University of Glasgow Centre for Virus Research (CVR) working with the Principal Investigators, Dr Stephen Carter and Prof David Bhella.
The applicant will make essential contributions to a research programme focused on understanding virus-host interactions using cryo-electron tomography (cryo-ET) combined with cryogenic correlated light and electron microscopy (cryo-CLEM) and cryo-focused ion beam (cryo-FIB) milling. The project will focus on understanding the replication machinery of clinically important negative-sense RNA viruses. Specifically, the project will investigate the relationships between the virus replication machinery and cellular organelles, such as endoplasmic reticulum and mitochondria. The successful candidate will be self-motivated in designing and executing imaging experiments, and analysis of the data, collected using cutting edge cryo-electron tomography techniques and sub-tomogram averaging.
Main Duties and Responsibilities
Perform the following activities in conjunction with and under the guidance of the Principal Investigators (PIs), Dr Stephen Carter and Professor David Bhella.
1. Plan and conduct assigned research individually or jointly in accordance with the project deliverables and the research strategy of the MRC University of Glasgow Centre for Virus Research (CVR).
2. Document research output including analysis and interpretation of all data, maintaining records and databases, drafting technical/progress reports and papers as appropriate.
3. Develop and enhance your research profile and reputation and that of CVR, including contributing to publications of international quality in high profile/quality refereed journals, enhancing the research impact in terms of economic/societal benefit, and gathering indicators of esteem.
4. Contribute to the presentation of work at international and national conferences, at internal and external seminars, colloquia and workshops to develop and enhance our research profile.
5. Contribute to the identification of potential funding sources and to assist in the development of proposals to secure funding from internal and external bodies to support future research.
6. Collaborate with colleagues and participate in team/ group/ meetings/ seminars/ workshops across the CVR and wider community.
7. Contribute to the organisation, supervision, mentoring and training of undergraduate and/or postgraduate students and less experienced members of the project team to ensure their effective development.
8. Perform administrative tasks related to the activities of the research group and School, including Budgets/Expenditure.
9. Carry out modest Teaching activities [eg demonstrating etc.] and associated administration as assigned by the CVR Director and in consultation with the Principal Investigators.
10. Keep up to date with current knowledge and recent advances in the field/discipline.
11. Engage in continuing professional development activities as appropriate.
12. Undertake any other reasonable duties as required by the Director of the CVR and/or Principal Investigators
13. Contribute to the enhancement of the University’s international profile in line with the University’s Strategic Plan, World Changers Together.
For Appointment at Grade 7:
14. Perform the above duties with a higher degree of independence, leadership, and responsibility, particularly in relation to planning, funding, collaborating and publishing research, and mentoring colleagues.
15. Establish and sustain a track record of independent and joint published research to establish and maintain your expert reputation in the subject area. 16. Survey the research literature and environment, understand the research challenges associated with the project and subject area, and develop/implement a suitable research strategy.
These key tasks are not intended to be exhaustive but simply highlight a number of major tasks which the staff member may reasonably be expected to perform.
*In line with current Government guidance, the University of Glasgow is operating with restricted occupancy levels within University buildings. As a result, a degree of flexibility is required in terms of working hours/patterns and there will be occasions when the post holder will be required to work from home.*
***Please note that as part of your application you must address and demonstrate how you meet EACH of the essential/desirable criteria, point by point. ***
Qualifications
Essential
A1 Scottish Credit and Qualification level 10 (Honours degree or equivalent) in a biological science or other relevant subject. May be working towards a post-graduate qualification such as a Masters (Scottish Credit and Qualification Framework level 11) or PhD (Scottish Credit and Qualification Framework level 12).
Or
Equivalent professional qualifications in a relevant academic/research discipline, and experience of personal development in a similar role.
For Appointment at Grade 7
Essential
A2 Normally Scottish Credit and Qualification Framework level 12 (PhD) in cell biology, structural biology or related field, such as X-ray crystallography or NMR or alternatively possess the equivalent in professional qualifications and experience, with experience of personal development in a similar or related role(s).
Desirable at Grade 6
B1 Working towards or completed a PhD in cell biology, structural biology or related field, such as X-ray crystallography or NMR.
B2 Qualifications received or pending from internationally renowned institutions/laboratories.
Knowledge and Skills
Essential
C1 A strong background in structural biology data collection and image processing.
C2 Research creativity and cross-discipline collaborative ability as appropriate.
C3 Excellent interpersonal skills including team working and a collegiate approach.
C4 Excellent communication skills (oral and written), including public presentation and the ability to communicate complex concepts clearly and concisely.
C5 A high degree of competence in English scientific writing and speaking.
C6 Appropriate workload/time/project/budget/people management skills.
C7 IT and data analysis/interpretation skills as appropriate.
C8 Highly motivated, able to use initiative and quick to learn new techniques.
C9 Creative, flexible and pragmatic approach to solving research problems.
For Appointment at Grade 7
Essential
C10 Good team leadership skills including demonstrable supervisory skills.
Desirable at Grade 6/7
D1 Knowledge of correlated light and electron microscopy.
D2 Knowledge of image segmenting within 3D volumes.
D3 Laboratory data handling and management skills; for example, statistical analysis (Excel, R, Prism etc).
Experience
Essential
E1 Sufficient breadth and/or depth of knowledge in the specialist subject discipline and of research/teaching methods and techniques to work in virology, demonstrated through relevant work experience.
E2 Experience with operating a dual-beam cryo-FIB/SEM microscope with mammalian cells.
E3 Experience with IMOD, EMAN2, Relion, Amira and Chimera.
E4 Proven ability to deliver quality outputs (such as publications) in a timely and efficient manner.
E5 Experience preparing data for publication and writing publications.
E6 Evidence of an emerging track record of publications in a relevant field.
For Appointment at Grade 7
Essential
E7 Sufficient breadth and/or depth of knowledge in the specialist subject/discipline and of research/teaching methods and techniques to work within the subject area, as demonstrated through relevant post-doctoral work experience. This will include independence illustrated by identification of project objectives from assessment of the literature, the design/analysis of experiments, and the drafting of scientific publications.
E8 Established publication track record in a relevant field of research, including at least one as first author, in appropriate-impact international scientific journals.
Desirable at Grade 6/7
F1 Experience in aseptic tissue culture.
F2 Experience with writing and implementing scripts using Python etc.
F3 Experience with purification of viruses.
Desirable at Grade 7
F4 An emerging national or international reputation.
For enquiries regarding the post, please contact Dr Stephen Carter, Stephen.Carter@glasgow.ac.uk
Terms and Conditions
Salary will be on the University’s Research and Teaching Grade, level 6/7, £29,176 - £32,817/£35,845 - £40,322 per annum.
This post has funding up to 31 March 2023.
New entrants to the University will be required to serve a probationary period of 6 months.
The successful applicant will be eligible to join the Universities’ Superannuation Scheme. Further information regarding the scheme is available from the Superannuation Officer, who is also prepared to advise on questions relating to the transfer of Superannuation benefits.
All research and related activities, including grants, donations, clinical trials, contract research, consultancy and commercialisation are required to be managed through the University’s relevant processes (e.g. contractual and financial), in accordance with the University Court’s policies.
It is the University of Glasgow’s mission to foster an inclusive climate, which ensures equality in our working, learning, research and teaching environment.
We strongly endorse the principles of Athena SWAN, including a supportive and flexible working environment, with commitment from all levels of the organisation in promoting gender equality.
Vacancy Ref: 061867, Closing Date: 9 August 2021

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Deadline: 21-06-2024

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